I always wondered how long this network stuff would go on after meeting Barabasi at a NATO school on complex systems. It just keeps going and going and certainly seems to have lasted far longer than I had thought it would. Part of it, usefully, seems to have merged with the big data tsunami hitting just about everything. Still, though, it seems to me this is mostly about the statistics of artifacts, scale-free... whatever that means. Most biological interactions are probably meaningless, e.g., see the collected works of Sandy Johnson at UCSF on targets of specific transcription factors. So, even if the nodes and edges were all real, it is unclear how informative the statistics of neutral evolution interactions might be in gaining biological insight.

AuthorJan Skotheim