From the Manalis and Piel labs: http://jcb.rupress.org/content/211/4/733.full
Beautiful work by Son et al and Zlotek-Zlotkiewicz et al. who developed two more precise ways of measuring volume revealed that cells take up fluid to swell in mitosis. This helps them round up, possibly to make space for a nice spindle. Evgeny and I tried to write a decent summary here.
check it out in TIBS: http://www.cell.com/trends/cell-biology/abstract/S0962-8924%2815%2900193-2
Also, this review provides a bit more context than what is provided in the long form poem we wrote otherwise known as a nature letter. I hope the review helps! Also, Devon and Kurt are following this up and there is more to come on the subject (hopefully) shortly. The differential expression of genes with cell size is a bigger deal than the already big deal, IMHO, of cell size control.
I think this is destined to gain the thousand or so views of my reappointment talk. still, it would take a lot of globetrotting to give a seminar to 1000 people 50 at a time! I hope you like it (click here)
a very nice article from Bjorn Carey on our work analyzing the connection between growth and division in budding yeast
unexpectedly, Cln3 is not the answer...
Cell growth dilutes a cell cycle inhibitor, Whi5, while the cell cycle activator, Cln3, remains at constant concentration. When Whi5 is diluted below a critical concentration, cells enter the division cycle. Dilution of a cell cycle inhibitor is a new concept in cell biology and an elegant solution to the problem of coupling growth to division.
Read all about it here http://www.nature.com/nature/journal/vaop/ncurrent/full/nature14908.html?WT.ec_id=NATURE-20150924&spMailingID=49614214&spUserID=NDk5Njc4MjI2OTYS1&spJobID=763182077&spReportId=NzYzMTgyMDc3S0